CUMULATIVE CLINICAL EXPERIENCE FROM OVER A DECADE OF USE OF LEVOFLOXACIN IN COMMUNITY-ACQUIRED PNEUMONIA: CRITICAL APPRAISAL AND ROLE IN THERAPY

Cumulative clinical experience from over a decade of use of levofloxacin in community-acquired pneumonia: critical appraisal and role in therapy

Ayman M Noreddin1, Walid F Elkhatib2, Kenji M Cunnion3, George G Zhanel41Department of Pharmacy Practice, Hampton University, Hampton, VA, USA; 2Department of Microbiology and Immunology, Ain-Shams University, Cairo, Egypt; 3Department of Pediatrics, East Virginia Medical School, Norfolk, VA, USA; 4Department of Medical Microbiology and Infectious

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Carbohydrate ingestion induces differential autonomic dysregulation in normal-tension glaucoma and primary open angle glaucoma.

BackgroundIt is reported that glaucoma may be associated with vascular dysregulation.Normal tension glaucoma (NTG) and primary open angle glaucoma (POAG), which feature different intraocular pressure levels, may manifest differential features of systemic autonomic dysregulation.Methods and resultsWe investigated autonomic regulation to carbohydrate

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Exploring disability from the perspective of adults living with HIV/AIDS: Development of a conceptual framework

Abstract Background Since the advent of combination antiretroviral therapy, in developed countries HIV increasingly is perceived as a long-term illness.Individuals may experience health-related consequences of HIV and its associated treatments, a concept that may be termed disability.To date, a comprehensive framework for understanding the health-r

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Proteomic insights into extracellular vesicles in ALS for therapeutic potential of Ropinirole and biomarker discovery

Abstract Background Extracellular vesicles (EVs) hold the potential for elucidating the pathogenesis of amyotrophic lateral sclerosis (ALS) and serve as biomarkers.Notably, the comparative and longitudinal alterations in the protein profiles of EVs in serum (sEVs) and cerebrospinal fluid (CSF; cEVs) of sporadic ALS (SALS) patients remain uncharted.

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